PRODUCT

Thymosin Beta-4

No short description available.

Molecular Info

Chain Length:43 amino acids
Sequence Type:Thymosin peptide
Molecular Weight:4,963.44 Da
Amino Acid Sequence:Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Modification:N-terminal acetylation, naturally occurring in thymus

Research Indications

Tissuerepair

effective

Wound Healing Acceleration
Clinical trials show 67% complete healing vs 25% placebo in pressure ulcers
Post-Surgical Recovery
Enhanced tissue regeneration and reduced healing time in surgical wounds
Soft Tissue Injury Repair
Accelerated recovery in muscle, tendon, and ligament injuries

Cardiovascular

effective

Cardiac Protection Post-MI
Phase 2b trials show 43% reduction in infarct size when given within 6 hours
Coronary Artery Disease
Improved cardiac function and reduced adverse remodeling
Peripheral Vascular Disease
Enhanced angiogenesis and improved blood flow to affected tissues

Neuroprotection

effective

Stroke Recovery Enhancement
Improved neurological outcomes and functional recovery in animal models
Traumatic Brain Injury
Reduced brain edema and enhanced neural repair mechanisms
Spinal Cord Injury Support
Neuroprotective effects and functional recovery promotion

Interactions

TB-500

Synergistic

TB-500 is the bioactive fragment of Thymosin β4. Combined use provides full-length peptide benefits plus concentrated bioactive effects for enhanced tissue repair.

BPC-157

Synergistic

Complementary healing mechanisms - Tβ4 promotes cell migration and angiogenesis while BPC-157 enhances gastric protection and systemic healing.

Growth Hormone

Compatible

No direct interactions reported. Both promote tissue repair through different pathways and can be used together safely.

IGF-1

Compatible

Complementary growth factor effects without direct interaction. Both support tissue regeneration through distinct mechanisms.

Corticosteroids

Use Caution

Steroids may reduce Thymosin β4 effectiveness by inhibiting inflammatory responses necessary for optimal healing.

Anticoagulants

Monitor Combination

Tβ4 promotes angiogenesis which may affect bleeding risk. Monitor coagulation parameters when used with warfarin or similar agents.

NSAIDs

Requires Timing

High-dose NSAIDs may interfere with inflammatory processes necessary for Tβ4-mediated healing. Consider timing or reduced NSAID dosing.

Chemotherapy

Avoid Combination

Theoretical concern about promoting angiogenesis in cancer patients. Avoid use during active chemotherapy treatment.

Dosage Protocols

Acute Wound Healing:1.6 mgDaily
Cardiac Protection:42 mgSingle dose
Chronic Tissue Repair:6 mgTwice weekly
Neurological Recovery:30 mgThree times over 72 hours
General Regeneration:2-5 mgDaily or every other day
Research Protocol:0.6-14 mgAs per study design

Route:injectable

Reconstitution

Allow lyophilized powder to reach room temperature before reconstitution
Add bacteriostatic water slowly to the vial wall, avoiding direct contact with powder
Gently swirl (do not shake vigorously) until completely dissolved
Inspect solution for clarity - should be clear and colorless
Store reconstituted solution at 2-8°C and use within 14 days
For injection, use proper aseptic technique and rotate injection sites

Route:injectable

Thymosin Beta-4

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