PRODUCT

Epitalon

No short description available.

Molecular Info

Chain Length:4 amino acids
Sequence Type:Tetrapeptide
Molecular Weight:390.35 Da
Amino Acid Sequence:Ala-Glu-Asp-Gly
Modification:Synthetic analog of epithalamin from pineal gland

Research Indications

Anti Aging

most_effective

Telomere Extension
Activates telomerase to lengthen telomeres at microgram doses, extending cellular replicative lifespan
Cellular Rejuvenation
Reverses markers of cellular aging through low-dose regulatory signaling
Lifespan Extension
Animal studies show 25-33% lifespan increase using 30-40 μg/kg doses

Neuroprotection

effective

Pineal Function Restoration
Enhances pineal gland activity with microgram dosing, normalizing age-related melatonin decline
Neurogenesis Support
Upregulates neurogenic differentiation genes at nanogram concentrations
Retinal Protection
Clinical evidence shows 90% response rate using only 5μg per eye daily

Immunity

moderate

Thymus Regeneration
Restores thymus structure and function using physiological doses
Immune Surveillance
Enhances immune system through regulatory signaling at low concentrations
Reduced Immunosenescence
Counters age-related immune decline without excessive peptide exposure

Interactions

Melatonin

Synergistic

Both work through pineal pathways - Epitalon increases endogenous melatonin production, creating complementary circadian and anti-aging effects

Thymalin

Synergistic

Combined use in Russian protocols shows enhanced immunomodulation and geroprotective effects through complementary mechanisms

NAD+ Precursors

Compatible

No direct interaction - work through different anti-aging pathways (telomerase vs NAD+ metabolism)

Growth Hormone Peptides

Compatible

No known interactions - Epitalon works through telomerase/pineal pathways while GH peptides use pituitary axis

BPC-157

Compatible

Different mechanisms - can be used together safely for comprehensive regenerative support

Cortexin

Monitor Combination

Both have neuroprotective effects - monitor for enhanced cognitive effects and adjust dosing if needed

Semax/Selank

Compatible

No direct interactions - Epitalon focuses on cellular aging while these target neurocognitive function

Cancer Therapeutics

Unknown

Telomerase activation in cancer context requires careful consideration - consult oncologist before use

Dosage Protocols

Evidence-Based Protocol (Recommended):200-500μgDaily
Conservative Start:100μgDaily
Russian Clinical Equivalent:300μgDaily
Traditional Western (Anecdotal):5-10mgDaily
Ultra-Low Dose:50μgDaily

Route:injectable

Reconstitution

Clean vial tops with alcohol swab and allow to dry
For corrected dosing: Add 5ml bacteriostatic water to create appropriate concentration
For 10mg vial: Creates 2mg/ml solution - use 0.1ml for 200μg dose
Inject water slowly into peptide vial, aiming at the side wall
Gently swirl vial - do not shake vigorously to preserve peptide structure
Solution should be clear and colorless when properly mixed
Store reconstituted solution in refrigerator immediately
Use smaller syringes (0.3ml) for accurate microgram dosing

Route:injectable

Epitalon

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