PRODUCT

Cyclic Glycine-Proline

No short description available.

Chain Length:2 amino acids (cyclic)
Sequence Type:Cyclic dipeptide (2,5-diketopiperazine)
Molecular Weight:154.17 Da
Amino Acid Sequence:cyclo(Gly-Pro)
Modification:Cyclic structure formed by peptide bond between glycine and proline termini

Neurological

effective

Cognitive Enhancement
Higher cGP levels correlate with better memory retention in elderly. Increases BDNF and modulates AMPA receptors.
Neuroprotection
Protects neural cells from oxidative stress. Demonstrated efficacy in stroke and brain injury models.
Neurodegenerative Diseases
Clinical trials ongoing for Alzheimer's, Parkinson's, Rett syndrome, and Fragile X syndrome using cGP analogs.

Metabolic

effective

IGF-1 Regulation
Normalizes IGF-1 bioavailability - promotes activity when insufficient, inhibits when excessive.
Cardiovascular Support
Reduces blood pressure and improves vascular health markers in clinical observations.
Diabetes Support
Clinical trial showed improved vascular complications and metabolic markers in type-2 diabetes.

Recovery

effective

Stroke Recovery
Higher cGP/IGF-1 ratio associated with better clinical outcomes following stroke.
Healthy Aging
Maintaining higher cGP/IGF-1 ratio with age associated with preserved cognitive function.

IGF-1

Synergistic

cGP is a metabolite of IGF-1 and regulates its bioavailability by competing for IGFBP-3 binding - normalizes IGF-1 function

BPC-157

Compatible

Different mechanisms - BPC-157 promotes tissue repair while cGP modulates IGF-1 function

Semax

Compatible

Both have neuroprotective and nootropic effects through different pathways

Selank

Compatible

Complementary cognitive enhancement - Selank for anxiety, cGP for IGF-1 optimization

GH Secretagogues

Monitor Combination

Both affect growth hormone/IGF-1 axis - monitor for combined effects on IGF-1 levels

Resources