PRODUCT

CJC-1295 DAC (2 mg Vial)

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Quickstart Highlights

CJC-1295 DAC dosage protocols leverage this long-acting growth hormone-releasing hormone (GHRH) analog’s unique albumin-binding technology, which extends its half-life to approximately 6–8 days[1][2]. By stimulating pulsatile growth hormone (GH) release while preserving natural GH rhythms, CJC-1295 DAC can elevate GH levels 2–10 fold and IGF-1 levels 1.5–3 fold in human studies[3]. Benefits may include enhanced muscle growth and recovery, improved fat metabolism, better sleep quality, and anti-aging effects through sustained GH/IGF-1 axis activation[4][5]. This educational protocol presents a once-weekly subcutaneous approach using a practical dilution for clear insulin-syringe measurements.

Reconstitute: Add 1.0 mL bacteriostatic water → 2.0 mg/mL (2,000 mcg/mL) concentration.
Typical weekly dose: 2,000 mcg (2 mg) once weekly — the full vial per injection.
Easy measuring: At 2.0 mg/mL, 1 unit = 0.01 mL = 20 mcg on a U-100 insulin syringe; full dose = 100 units (1.00 mL).
Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.

Reconstitution

Draw 1.0 mL bacteriostatic water with a sterile syringe.
Inject slowly down the vial wall; avoid foaming or direct stream onto the powder.
Gently swirl/roll until dissolved (do not shake vigorously).
Label with reconstitution date and refrigerate at 2–8 °C (35.6–46.4 °F) , protected from light.
Label with reconstitution date and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.

Protocol Overview

Goal:Elevate endogenous GH and IGF-1 levels to support muscle growth, fat metabolism, recovery, and anti-aging research[4][5].
Schedule:Weekly subcutaneous injections for 8–12 weeks.
Dose:2,000 mcg (2 mg) once weekly — one full vial per injection.
Reconstitution:1.0 mL per 2 mg vial (2.0 mg/mL) for accurate unit measurements.
Storage:Lyophilized frozen; reconstituted refrigerated; avoid repeated freeze–thaw.

Dosage Protocols

Standard Dose:2,000 mcg (2 mg) once weekly[7].
Frequency:Once per week (subcutaneous).
Cycle Length:8–12 weeks; optional 4-week break between cycles.
Timing:Evening administration (pre-bed) may synergize with natural nocturnal GH release; rotate injection sites weekly[6].

Storage Instructions

Lyophilized:Store at −20 °C (−4 °F) in dry, dark conditions; minimize moisture exposure.
Reconstituted:Refrigerate at 2–8 °C (35.6–46.4 °F); use within 4 weeks and avoid freeze–thaw[8].

Important Notes

Practical considerations for consistency and safety.

Use new sterile insulin syringes for each injection; dispose in a sharps container[9].
Rotate injection sites weekly (abdomen, thighs, upper arms) to reduce local irritation[10].
Inject on an empty stomach (at least 2 hours after a meal) as elevated blood sugar may blunt GH release.
Document weekly dose, date, and site rotation to maintain consistency.

How It Works

CJC-1295 DAC is a modified 30-amino-acid GHRH analog conjugated to a Drug Affinity Complex (DAC) that covalently binds to serum albumin after injection[1]. This albumin binding dramatically extends the peptide’s half-life from minutes to approximately 6–8 days, enabling once-weekly dosing[2]. CJC-1295 binds to GHRH receptors on pituitary somatotrope cells, amplifying GH synthesis and pulsatile release. Importantly, it elevates basal GH levels while preserving the natural rhythm of GH pulses — the frequency and amplitude remain intact[11]. Clinical trials demonstrate sustained 2–10 fold increases in GH and 1.5–3 fold increases in IGF-1, with elevated IGF-1 persisting for up to 28 days after multiple doses[3].

Lifestyle Factors

Pair with a balanced, protein-forward diet tailored to energy and recovery needs.
Combine resistance training and aerobic activity to reinforce anabolic and metabolic adaptations.
Prioritize sleep quality — GH is primarily secreted during slow-wave sleep[6].
Avoid eating 2+ hours before injection to optimize GH release response.

Injection Technique

Clean the vial stopper and skin with alcohol; allow to dry completely.
Pinch about an inch of skin at the injection site (lower abdomen, outer thigh, or upper arm)[10].
Insert the needle at a 90° angle into the pinched fold (use 45° if minimal subcutaneous fat)[10].
Depress the plunger fully, then withdraw the needle and dispose in a sharps container.
Rotate sites weekly to prevent lipohypertrophy — for example, alternate between left and right abdomen[10].

Benefits and Side Effects

Benefits

Sustained elevation of GH and IGF-1 levels supporting muscle growth, recovery, and lean body composition[4][5].
Enhanced fat metabolism and potential reduction in visceral adiposity[12].
Improved sleep quality — GHRH analogs may have somnogenic effects, increasing deep slow-wave sleep[6].
Preserves natural GH pulsatility unlike exogenous GH administration[11].

CJC-1295 DAC (2 mg Vial)

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