PE-22-28 is a synthetic heptapeptide (sequence: GVSWGLR) derived from the sortilin propeptide, engineered as a potent and selective antagonist of TREK-1 potassium channels[4]. Preclinical studies demonstrate rapid antidepressant-like effects, enhanced neurogenesis, and neuroprotection with a favorable safety profile showing no cardiac or metabolic side effects[2][3]. This educational protocol presents a once-daily subcutaneous approach with gradual titration.
- 재구성: 3.0 mL의 박테리아 정지수를 추가하세요 → ~3.33 mg/mL 농도.
- 일일 일반 범위: 하루 50–200 µg (8–16주 동안 점진적 증량).
- 간편한 측정: 3.33 mg/mL에서 1 단위 = 0.01 mL ≈ 33.3 µg는 U-100 인슐린 주사기에 해당합니다.
- 저장: 동결 건조: −20 °C (−4 °F)에서 냉동; 재구성 후 2–8 °C (35.6–46.4 °F)에서 냉장; 빛으로부터 보호.
